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KMID : 0378019750180091195
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New Medical Journal
1975 Volume.18 No. 9 p.1195 ~ p.1201
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Comparison of Dermal Reaction with VBS and KST Antigens of Clonorchis sinensis in Reference to Sensitivity and Specificity
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安泳謙/Ahn, Yung-Kyum
蘇鎭琸/韓載琴/Soh, Chin-Thack/Han, Jai-Kum
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Abstract
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Intradermal test is usually employed for diagnosis of the Clonorchis sinensis infection, specially for mass survey in an endemic area. To evaluate and assess the sensitivity and specificity of antigens of Clonorchis sinensis, VBS antigen (prepared by National Institute of Health, Republic of Korea) and KST antigen (prepared by Professor Sawada, T., Gumma University, Japan), intradermal tests with the antigens were carried out in an endemic area along Mangyung river during summer months of 1974.
The results are summarized as follows:
1. Egg positives of Clonorchis sinensis by formalin-ether concentration method were 125(25.5%) among 490 examined.
2. Positive rate of dermal reaction with VBS antigen was 34.7% (170 out of 490), which exceeded 9.2% than egg positive rate. VBS negatives were 8(6.4%) among 125 egg positives, and VBS positives were 53(14.5%) among 365 egg negatives.
3. Positive rate of dermal reaction with KST antigen was 27. 3% (134 out of 490), which exceeded 1.8% than egg positive rate. KST negatives were 12(9.6%) among 125 egg positives, and KST positives were 21(5.8%) among 365 egg negatives.
4. The sensitivities were; 93.6% with VBS antigen and 90.4% with KST antigen. The specificities were; 85.5% with VBS antigen and 94.3% with KST antigen.
The overall agreementd were 87.6% with VBS antigen and 93.7% with KST antigen.
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KEYWORD
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